Articles

ORTHOVISC

Safety and Efficacy

Efficacy and Safety of Intraarticular Sodium Hyaluronate in Knee Osteoarthritis - Clinical Orthopedics and Related Research, Brandt et al. 2001
226 patients at 10 sites were randomized to receive either ORTHOVISC or saline. This study proves that ORTHOVISC is well tolerated and produces statistically and clinically significant reduction of OA symptoms in patients with mild to moderate knee osteoarthritis.

Clinical Effects of Intraarticular Injection of High Molecular Weight Hyaluronan (ORTHOVISC) in Osteoarthritis of the Knee: Randomized, Controlled, Multicenter Trial - The Journal of Rheumatology, Neustadt et al. 2005
372 patients at 24 sites were randomized to receive either ORTHOVISC or arthrocentesis. This study proves that ORTHOVISC is a safe product for treatment of knee osteoarthritis and that ORTHOVISC is effective in reducing the pain and symptoms associated with OA of the knee.

Additional ORTHOVISC Trials

The safety and efficacy of intraarticular hyaluronan with/without corticosteroid in knee osteoarthritis. - Rheumatology International, Ozturk et al. 2006
This study compared two patient groups – one treated with ORTHOVISC alone and one treated with ORTHOVISC and steroid (triamcinolone), ORTHOVISC and steroid was superior to ORTHOVISC alone for early pain relief.